Endocrine Abstracts

Introduction: Vitamin D is a hormone that acts through the Vitamin D receptor (VDR) not only on the skeletal system but on a great number of target tissues, including thyroid gland. In recent years the association of vitamin D with autoimmune thyroid diseases (AITD), has been suggested.VDR gene polymorphisms had been associated with an increased risk of AITD. In addition a recent meta-analysis showed that AITD patients had lower level of 25-hydroxyvitami...

Introduction: TSH-secreting adenomas represent <2% of pituitary tumors. Surgery and/or radiotherapy are primary treatment options. Somatostatin analogues and also dopamine agonists, represent valuable alternatives or adjuvant therapies.Objective: To report a case of euthyroidism and tumor stability achieved in a TSH-secreting pituitary macroadenoma, treated with octreotide-LAR, as first line therapy, and then added cabergoline. To review the efficacy...

Introduction: Incidence of Digestive NETs (DNETs) has increased in the last 40 years. Visceral obesity, metabolic syndrome (MetS) and insulin resistance (IR) have been associated with several types of cancer.Aim: To evaluate possible associations of obesity, hyperinsulinemia and IR with well-differentiated (WD) DNETs through a case control study.Materials and methods: Ninety-six patients with gastrointestinal (75.0%) and pNET (22.9...